Temporal Chondroblastoma with a Novel Chromosomal Translocation (2;5) (q33;q13)

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Temporal Chondroblastoma with a Novel Chromosomal Translocation (2;5) (q33;q13)

The case of a 51-year-old man with a large temporal mass is presented. The mass eroded the floor of the middle fossa medially to the sphenoid sinus. A combined approach with neurosurgery and otolaryngology was performed to achieve maximal resection of the mass. Pathology was typical for chondroblastoma: a rare, benign but locally invasive chondroid tumor. Genetic testing revealed a translocatio...

متن کامل

LMO2 at 25 years: a paradigm of chromosomal translocation proteins

LMO2 was first discovered through proximity to frequently occurring chromosomal translocations in T cell acute lymphoblastic leukaemia (T-ALL). Subsequent studies on its role in tumours and in normal settings have highlighted LMO2 as an archetypical chromosomal translocation oncogene, activated by association with antigen receptor gene loci and a paradigm for translocation gene activation in T-...

متن کامل

Chondroblastoma of the temporal bone.

Chondroblastomas are highly destructive tumors that are derived from immature cartilage cells. The occurrence of this tumor in the temporal bone or skull base is uncommon. Approximately 70 cases have previously been reported, several of which have involved the temporomandibular joint (TMJ). We report here the case of a 67-year-old woman who presented with right-sided mixed hearing loss, a right...

متن کامل

A Chromosomal Translocation Causing Overproduction

The CYC7-1 mutation in the yeast Saccharomyces cereuisiae causes the production of approximately 30 times the normal amount of iso-2-cytochrome c. Genetic analysis established that the CYC7-I mutation is a reciprocal translocation involving the left arm of chromosome V and the right arm of chromosome XVZ. The chromosome V arm was broken adjacent to the gene CYC7, which determines the primary st...

متن کامل

The prevalence of chromosomal translocation t (1; 4) (p21; p14) in Iranian patients with mental disability

Introduction: Intellectual disability or intellectual retardation is a condition in which total mental functioning is distinctively below average and there are disabilities in adaptive behaviors during growth. According to the definition of American Mental Disability Community in 1992 a person is considered intellectually disabled if he or she has an IQ (intelligence quotient) of less than 70...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Skull Base Reports

سال: 2011

ISSN: 2157-6971,2157-698X

DOI: 10.1055/s-0031-1275638